Reference type

Journal Article
 

Record Number

33

Author

Sagild, I.K.; Haresnape, J.M.

Year

1987

Title

The status of Newcastle disease and the use of V4 vaccine in Malawi

Journal

Avian Pathology

Volume

16

Pages

165-176

Label

Journal

Keywords

Malawi, Newcastle disease, V4 vaccine,

Notes

Data on the incidence of Newcastle disease in Malawi obtained from various sources including serological surveys, questionnaires and interviews, as well as statistics on laboratory-confirmed cases, showed the disease to be widespread throughout the country. Chickens vaccinated with La Sota and Komarov vaccine strains were often inadequately protected against the disease, especially those under smallholder management. Trials involving laboratory chickens and chickens under both intensive and smallholder management showed that V4 vaccine, given by eye-drop, drinking water and oral droplet methods, induced an antibody response sufficient to protect birds against challenge with virulent field isolates of Newcastle disease virus. V4 is recommended as an alternative to La Sota and Komarov vaccines, particularly for small holder flocks, because of its thermostability, its ease of administration and its transmissibility. Large scale use of V4 appears to have reduced the incidence of Newcastle disease in rural parts of Malawi.