Reference type

Journal Article
 

Record Number

44

Author

Tantaswasdi, Urasri; Danvivatanaporn, Jintana; Siriwan, Porntip; Chaisingh, Arunee; Spradbrow, P.B.

Year

1992

Title

Evaluation of an oral Newcastle disease vaccine in Thailand

Journal

Preventive Veterinary Medicine

Volume

12

Pages

87-94

Label

Journal

Keywords

Food vaccine, Newcastle disease, Thailand, V4 vaccine

Notes

Laboratory chickens were vaccinated against Newcastle disease by feeding them with the avirulent, heat-resistant V4 strain of Newcastle disease virus applied to various grains. In one experiment, chickens receiving vaccine on paddy (unhusked) rice and on cooked white rice when 4 and 6 weeks of age were protected against contact challenge with a viscerotropic, velogenic strain of Newcastle disease virus. The vaccine virus spread to in-contact chickens and these also resisted challenge. In another experiment, chickens receiving the same vaccine on the same grains were not protected. The chickens in the unsuccessful trial were younger, had higher levels of maternal antibody and were kept on wire mesh instead of on solid floors, thereby minimising transmission of the vaccine virus. Strain V4 was an effective vaccine when given intranasally or in drinking water but V4 vaccine supplied on uncooked white rice and on uncooked broken brown rice was not protective. Oral vaccine delivered on paddy or cooked white rice could provide a practical method of protecting free-range village chickens against Newcastle disease.